TDSSkiller HELP! (10 point best answer)?

i’m running a TDSSKILLER kaspersky and it determined ROOTkit.win32.tdss.tdl4 as well as we tried that will text the idea to quarantine but whenever once i reactivate laptop as well as operate that search within for a second time, this specific rootkit will forever seem.can i cure the following get back this

Run your current kaspersky electricity inside safemode also it will clear the infectivity.